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Fluorescent Nanowire Heterostructures as a Versatile Tool for Biology Applications

Author:
  • Karl Adolfsson
  • Henrik Persson
  • Jesper Wallentin
  • Stina Oredsson
  • Lars Samuelson
  • Jonas Tegenfeldt
  • Magnus Borgström
  • Christelle Prinz
Publishing year: 2013
Language: English
Pages: 4728-4732
Publication/Series: Nano Letters
Volume: 13
Issue: 10
Document type: Journal article
Publisher: The American Chemical Society (ACS)

Abstract english

Nanowires are increasingly used in biology, as sensors, as injection devices, and us model systems for toxicity studies. Currently, in situ visualization of nanowires in biological media is done using organic dyes, which a;:e prone to photobleaching, or using microscopy methods which either yield poor resolution or require a sophisticated setup. Here we show that inherently fluorescent nanowire axial heterostructnies c:an be used to localize and identify nanowires in cells and tissue; By synthesizing GaP GaInP nanowire heterostructures, with nonfluorescent GaP segments and fluorescent GaInP segments, we created a barcode labeling system enabling the distinction of the nanowire morphological and chemical properties using fluorescence microscopy. The GaInP photoluminescence stability, combined with the fact that the nanowires can be coated with different materials while retaining their fluorescence, make these nanowires promising tools for biological and nanotoxicological studies.

Keywords

  • Nano Technology
  • Nanowires
  • fluorescence
  • photoluminescence
  • photobleaching
  • cells
  • toxicology

Other

Published
  • Neuronano Research Center (NRC)
  • ISSN: 1530-6992
Stina Oredsson
E-mail: stina [dot] oredsson [at] biol [dot] lu [dot] se

Professor

Functional zoology

+46 46 222 94 97

B-C208

4

Principal investigator

LUCC - Lund University Cancer Centre

Research group

Animal Physiology

Projects

Cell proliferation

Doctoral students and postdocs

PhD Students, main supervisor

Wendy Soria Sotillo

PhD Students, assistant supervisor

Atena Malakpour Permlid