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International symposium on respiratory systems in gram-positive bacteria

11–12 April 2019, Lund, Sweden
Bacilli, Corynebacteria, Enterococci, Listeria, Staphylococci, Streptococci, Streptomycetes and Mycobacteria


The symposium is devoted to the composition, function, and assembly of respiratory systems, especially terminal oxidases, in aerobic Gram-positive bacteria. Many of these bacteria are of large medical or industrial importance.


Sessions I & II are open to the public, sessions III & IV require registration.

Thursday April 11, 2019, Department of Biology, Lecture hall in Biology building A, Sölvegatan 35, Lund
Session I – Respiratory supercomplexes
13:15–14:15 Leonid Sazanov (Institute of Science and Technology, Austria) Structure and function of respiratory complex I and supercomplexes
Keynote lecture and Department of Biology lecture
14:30–15:00 Ana Melo (Portuguese Infrastructure of Biological Data, Oeiras, Portugal) Respiratory supercomplexes of bacteria in perspective
15:00–15:20 Coffee/Tea  
15:20–15:50 Emma Berta Gutiérrez Cirlos (Universidad Nacional Autónoma de México, Iztacalka Tlalnepantla, Mexico) Are respiratory supercomplexes associated with other proteins in Bacillus subtilis membranes?
15:50–16:20 Martin Högbom (Stockholm University, Sweden) Structure and composition of the obligate mycobacterial III2IV2 respiratory supercomplex
16:20–16:45 Refreshments  
Session II – Extracellular electron transfer
16:45–17:15 Samuel Light (University of California, Berkeley, USA) Characterization of a branched extracellular electron transport chain in diverse Firmicutes
17:15–17:45 Galina Pankratova (Lund University, Sweden) Extracellular electron transfer features of Enterococcus faecalis
Evening events, for registered participants only
18:15 Visit to Skissernas museum (Museum of Artistic Process and Public Art)  
19:15 Dinner  
Friday April 12, 2019, Gamla Biskopshuset, Biskopsgatan 1, Lund
Session III – Respiratory enzyme biogenesis and metal cofactor metabolism
09:30–10:30 Eric Skaar (Vanderbilt University Medical Center, USA) How Gram positive bacteria solve the heme paradox
Keynote lecture
10:30–11:00 Coffee/Tea  
11:00–11:30 Michael Bott (Forschungszentrum Jülich, Germany) Assembly factors of the cytochrome bc1-aa3 supercomplex of Actinobacteria
11:30–12:00 Nick Le Brun (University of East Anglia, Norwich, UK) Copper trafficking and detoxification in Bacillus subtilis
12:00–12:30 Delphine Lechardeur (National Institute of Agronomic Research, Jouy en Josas, France) Strategies of heme management in Gram-positive bacterial pathogens
12:30–13:30 Lunch  
13:30–14:00 Lars Hederstedt (Lund University, Sweden) Cytochrome a oxidase assembly factors in Bacillus subtilis
Session IV – Physiological aspects of respiratory metabolism
14:00–14:30 Claes von Wachenfeldt (Lund University, Sweden) Redox sensing by Rex family repressors
14:30–15:00 Coffee/Tea  
15:00–15:30 Philippe Gaudu (National Institute of Agronomic Research, Jouy en Josas, France) Are respiratory components attractive antibiotic targets to limit pathogen infection? Case of an opportunistic pathogen; Streptococcus agalactiae
15:30–16:00 Michael Berney (Albert Einstein College of Medicine, New York, USA) Suffocating persistent Mycobacterium tuberculosis
End of the symposium sponsored by the Carl Tesdorpf Foundation
The Hederstedt colloquium, Gamla Biskopshuset, Biskopsgatan 1, Lund
16:15 Introduction & drinks  
16:45 Events  
18:30 Dinner  

A net of mycel with green dots in the ends.
Streptomyces coelicolor. Photo: Fanny Passot
Page Manager:

Organizer & contact person

Lars Hederstedt
Molecular Cell Biology

Telephone: +46 46-222 86 22
E-mail: Lars [dot] Hederstedt [at] biol [dot] lu [dot] se

The programme as a pdf (141 kB)