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REDOX regulation of mitochondrial function in plants

Author:
  • Estelle Giraud
  • Olivier Van Aken
  • Vindya Uggalla
  • James Whelan
Publishing year: 2012-02
Language: English
Pages: 80-271
Publication/Series: Plant, Cell and Environment
Volume: 35
Issue: 2
Document type: Journal article
Publisher: Wiley-Blackwell

Abstract english

Mitochondrial components dynamically change in response to environmental and developmental cues. However, the regulatory pathways that underlie these changes are largely unknown. A global analysis of changes in mitochondrial components at the transcript, protein and metabolite levels was undertaken, to gain a greater insight into how mitochondrial functions are regulated and respond to various internal or external cues. At the transcript level, large-scale changes in groups of genes suggest the presence of co-regulatory mechanisms for these components. Furthermore, the pathways that regulate these changes appear to be integrated into regulatory pathways that alter a variety of functions in cells. However, the changes in transcripts are not always observed at the protein or the metabolite level. This is likely to be due to post-transcriptional levels of regulation and also the fact that in-depth profiles, which have been obtained for transcripts from a variety of studies, are currently not available for proteins and metabolites. Thus, while transcripts for genes give us a picture of what the cells are 'thinking' in relation to mitochondrial components, some of these responses may be lost in translation.

Keywords

  • Biochemistry and Molecular Biology
  • Gene Expression Regulation, Plant
  • Metabolomics
  • Mitochondria
  • Oxidation-Reduction
  • Oxidative Stress
  • Plants
  • Proteomics
  • Stress, Physiological
  • Transcriptome

Other

Published
  • ISSN: 0140-7791
Olivier van Aken
E-mail: olivier [dot] van_aken [at] biol [dot] lu [dot] se

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Molecular Cell Biology

+46 46 222 94 13

B-A330

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Plant Biology

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