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Integrative epigenomic analysis of differential DNA methylation in urothelial carcinoma.

  • Mattias Aine
  • Gottfrid Sjödahl
  • Pontus Eriksson
  • Srinivas Veerla
  • David Lindgren
  • Markus Ringnér
  • Mattias Höglund
Publishing year: 2015
Language: English
Publication/Series: Genome Medicine
Volume: 7
Issue: 1
Document type: Journal article
Publisher: BioMed Central

Abstract english

Urothelial carcinoma of the bladder (UC) is a common malignancy. Although extensive transcriptome analysis has provided insights into the gene expression patterns of this tumor type, the mechanistic underpinnings of differential methylation remain poorly understood. Multi-level genomic data may be used to profile the regulatory potential and landscape of differential methylation in cancer and gain understanding of the processes underlying epigenetic and phenotypic characteristics of tumors.


  • Cancer and Oncology


  • Urothelial Cancer Genomics
  • Urological research, Malmö
  • ISSN: 1756-994X
Markus Ringnér
E-mail: markus [dot] ringner [at] biol [dot] lu [dot] se

Research engineer

Molecular Cell Biology


Sölvegatan 35, Lund