Genetic Analysis I BIOR59
The course is offered spring term period 1a. The medium of instruction is English.
In the courses Genetic analysis I and Genetic analysis II, the students are trained in areas which are of great importance in several biological disciplines. Whenever genetic data are used, in research and practical applications, the methods introduced in these courses are useful. This applies to the analysis of marker data as well as of complete sequences. Examples of such areas are association mapping in human and medical genetics as well as in plant and animal breeding. In these fields, both marker data and quantitative genetics are of an utmost importance.
Genetic analysis I is an advanced course covering transmission genetics (including linkage analysis), quantitative genetics and population genetics. It is assumed that the students already have passed a basic course in genetics. The part covering transmission genetics includes both Mendelian and non-Mendelian phenomena. In particular, the students are trained to deduce modes of inheritance from experimental crosses as well as from pedigree data. Another important part is linkage analysis and mapping, where among other things the concept of map-function is introduced. The section in population genetics covers parts of the classical foundations of this subject. Mostly, this section concerns the effect of selection and random effects on allele and genotype frequencies. Through the whole course a strong emphasis is put on problem solving.
Course literature 2021
Introduction to Genetic Analysis, 11 edition, Griffiths AJF, Wessler SR, Carroll SB, Doebley J. 2015.Freeman