Cellular and Molecular Immunology BIOR75
The course is offered for the last time spring term 2021.
The course Immunology and Infection Biology will replace this course spring term 2022. The medium of instruction is English.
Why study immunology?
The role of our immune system is to defend us against microbial infection, but the immune system is involved in many other physiological processes. This fascinating system is composed of a large number of cells, which both patrol our body by circulating in the blood and reside in various tissues. The cells have different kinds of expertise, each performing distinct functions, and collaborate to form an efficient and effective defense system to fight infections. The collaboration involves intricate interactions between cells causing exchange of signals that together tailor an appropriate response to any given microbe.
However, dysregulation of the immune response may lead to severe consequences in the form of autoimmunity, chronic unresolved inflammation or failure to kill tumor cells. Most of the diseases in humans involve the immune system. Thus, to study immunology is highly relevant for a future career in any discipline of human health, from the laboratory to pharmaceutical and biotech companies to clinical applications. Immunology is a fast-evolving field and this course aims to familiarize the student with the most recent and exciting developments.
Why choose this course?
The level of ambition is set high: the aim is to take the participant way beyond anecdotal knowledge of the immune system and expose the student to current immunological research. The student will develop skills in critical reading and understanding of original research articles, a skill-set that is transferrable to many other fields of study.
The focus is on the molecular and cellular basis of the adaptive immune response, which is mediated by lymphocytes. You will learn how these cells are generated and how they communicate, differentiate and function to eliminate invading microbes. Other areas of focus are regulation of the immune system in the normal steady state, myeloid cells and their role in infections and inflammatory diseases, hypersensitivity and autoimmunity and tumor immunology. The lecturers are obtained from different faculties and experts in their respective field.
The theoretical parts of the course are treated both in lectures and in group exercises in the form of literature seminars. The first weeks provide a general introduction to the immune system. Here the basic concepts and principles are introduced and will prepare you for the rest of the course. This second part of the course is divided into several themes, each partnered with a literature seminar to develop deeper understanding of the topic. Training in flow cytometric analysis will be given through a computer lab and associated lecture.
A written exam will be performed at the end of the course. Additional requirements are laboratory reports approved by laboratory teachers and active participation at group exercises & literature seminars.
Course literature 2021
Janeway’s Immunobiology; 9th ed. (2016) Murphy, Garland Publishing Inc.