Lund University is celebrating 350 years.


Javascript is not activated in your browser. This website needs javascript activated to work properly.
You are here

The challenges of integrating oxidative stress into life history biology.

  • Caroline Isaksson
  • Ben Sheldon
  • Tobias Uller
Publishing year: 2011
Language: English
Pages: 194-202
Publication/Series: BioScience
Volume: 61
Issue: 3
Document type: Journal article
Publisher: American Institute of Biological Sciences

Abstract english

It has been proposed that the molecular and physiological systems that regulate biological functions impose costs and constraints that are fundamental to the understanding of variation in life histories. In particular, studies of oxidative stress emphasize how evolutionary contingency can impose novel trade-offs for organisms, and how this may create or eliminate functional linkages between traits. Here, we critically assess the conceptual and empirical basis for these claims and what they mean for the study of life-history variation. Two key challenges are to go beyond the current focus on single components of regulatory systems, assessed at single points in time, and to establish the importance of trait- and stage-specific nutrient requirements for the functional linkage between life-history traits. Furthermore, future progress will critically depend on the replication of laboratory studies in natural settings to target the complexity of trade-off regulation in the wild.


  • Biological Sciences


  • ISSN: 0006-3568
Tobias Uller
E-mail: tobias.uller [at]


Evolutionary ecology

+46 46 222 30 94


Sölvegatan 37, Lund


Research group

Experimental Evolution, Ecology & Behaviour


Doctoral students and postdocs

I am currently about to move to Lund from University of Oxford. For details about DPhil students and postdocs in my previous research group based at the Edward Grey Institute, please click here

Downloads & links

CV (pdf; 241 kB)