My primary interest is understanding genetic and genomic mechanisms related to fungal host interactions (parasitic as well as symbiotic). Typically I am applying genomics and transcriptomics approaches coupled with bioinformatics analyses to provide novel insights into fungal host interactions. I have been studying the infection biology and evolution of parasitism among nematode-trapping fungi.
I got my PhD at Microbial Ecology, Lund University 2002 with professor Anders Tunlid as supervisor. I worked briefly as senior scientist at the bioinformatics company BioBridge Computing AB. I later did my post doc at the European Bioinformatics Institute (EBI). I returned to Microbial Ecology and am now working with genome evolution of nematode-trapping fungi and the symbiosis of ectomycorrhizal fungi
I am also working together with Katarina Hedlund, Sandeep Kushwaha, Tejashwari Meerupati, and Lokeshwaran Manoharan on a targeted metagenomics project to study the functional diversity in soil.
I support bioinformatics primarily related to next generation sequencing and evolution through the network Bioinformatics Infrastructure for Life Sciences (BILS) and I am active in the workshop on Genomics. I am a member of the steering committee in the Geneco research school that forges links between evolution, ecology and genomics.
(fetched from Lund University's publications database)
- Captured metagenomics: large-scale targeting of genes based on 'sequence capture' reveals functional diversity in soils.
- Cell periphery-related proteins as major genomic targets behind the adaptive evolution of an industrial Saccharomyces cerevisiae strain to combined heat and hydrolysate stress
- MetCap: a bioinformatics probe design pipeline for large-scale targeted metagenomics
- NBSPred: A support vector machine-based high throughput pipeline for plant resistance protein NBSLRR prediction.
- The carbon starvation response of the ectomycorrhizal fungus Paxillus involutus.
- Paralysis of nematodes: shifts in the transcriptome of the nematode-trapping fungus Monacrosporium haptotylum during infection of Caenorhabditis elegans
- The genome of Laccaria bicolor provides insights into mycorrhizal symbiosis
- Transcriptional analysis of the pheromone gland of the turnip moth, <i>Agrotis segetum</i> (Noctuidae), reveals candidate genes involved in pheromone production.
- CoGenT++: an extensive and extensible data environment for computational genomics
- Comparison of gene expression in trap cells and vegetative hyphae of the nematophagous fungus Monacrosporium haptotylum
- Expansion of the BioCyc collection of pathway/genome databases to 160 genomes
- Measuring genome conservation across taxa: divided strains and united kingdoms
- Low genetic diversity among isolates of the nematode-trapping fungus Duddingtonia flagrans: evidence for recent worldwide dispersion from a single common ancestor
- PHOREST: a web-based tool for comparative analyses of expressed sequence tag data
- Robustness of metabolic maps
- Transcriptional responses of Paxillus involutus and Betula pendula during formation of ectomycorrhizal root tissue